Annexin V (FL): sc-4252

Annexin V (FL), a fluorescently labeled variant of the protein Annexin V, serves as an essential tool in the study of cellular apoptosis and other dynamic cellular processes related to phospholipid signaling and membrane changes. Annexin V is a cellular protein known for its high affinity for phosphatidylserine (PS), a phospholipid that translocates from the inner to the outer leaflet of the cell membrane during early apoptosis. By conjugating Annexin V with a fluorescent label, researchers can visually track and analyze this translocation event, enabling the real-time observation of apoptotic processes under a fluorescence microscope. This capability makes Annexin V (FL) particularly valuable in research focused on the mechanisms of cell death and survival, as well as in studies investigating the effects of various environmental or genetic factors on cellular apoptosis. The fluorescence labeling does not significantly alter the binding properties of the protein, thus providing an accurate and effective means of detecting apoptosis without disrupting cellular function. Through the use of this fluorescent tool, scientists can quantitatively assess apoptosis in a variety of cell types, facilitating a deeper understanding of disease mechanisms, cellular aging, and the efficacy of potential regulatory compounds on the apoptotic pathways.